Cholesterol attenuates cytoprotective effects of phosphatidylcholine against bile salts
Abstract Bile salts have potent detergent properties and damaging effects on cell membranes, leading to liver injury.However, the molecular mechanisms for the protection of hepatocytes against bile salts are not fully understood.In this study, we demonstrated that the cytotoxicity of nine human major bile salts to HepG2 cells and primary human hepa